Saturday, May 11, 2013

What Space Does to Each of Your Five Senses

Commander of the International Space Station and awesome-stronaut Chris Hadfield just finished a weeklong series called ?Senses in Space,? where he describes what spending a long time in space does to each of your perceptions. And apparently, space is generally pretty bad for you. In the following five videos, Hadfield talks about blurred vision, loss of taste, and other unpleasant effects of the low-gravity environment?but all with his characteristic good cheer.

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Source: http://feeds.gawker.com/~r/gizmodo/full/~3/cVUttqYOMss/what-space-does-to-each-of-your-five-senses-500146813

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Friday, May 10, 2013

IMS: US medicine spending shows rare dip in 2012

TRENTON, N.J. (AP) ? Spending on prescription medicines in the U.S. fell for the first time in decades last year, slipping as cash-strapped consumers continued to cut back on use of health care services.

Patients also benefited from a surge of new, inexpensive generic versions of widely used drugs for chronic conditions like high cholesterol, according to a new report.

Total spending on medications dropped to $325.8 billion last year from $329.2 billion in 2011. Likewise, average spending per person on medicines fell by $33, to $898 last year, according to the report from the IMS Institute for Healthcare Informatics.

"That's the first time IMS has ever measured the decline in the 58 years we've been monitoring drugs," Michael Kleinrock, director of research development at the institute, told The Associated Press.

Factors behind last year's drop in drug spending include positive trends such as more use of cheap generic pills and flukes such as a fairly mild cold and flu season in early 2012. But there also was a big negative: people rationing their own health care.

IMS found affordability of health care remains a big problem for many Americans, with growing out-of-pocket costs forcing people to go without needed doctor visits, medicines and other treatments.

For some, that was because they lost jobs or homes during the worst recession in decades. But higher costs also are hitting many employed people who have health insurance.

Employers have been raising health costs for their workers well above the inflation rate, through higher copayments, premiums and deductibles. Many commercial insurance plans now have annual deductibles ? the amount a patient must pay before insurance kicks in ? that exceed $1,000, Kleinrock said.

The number of insured people with consumer-directed plans, where patients face very high deductibles and sometimes pay 20 percent of costs after that, has jumped from about 8 percent in 2008 to 19 percent last year. Now many folks insured through their jobs have such plans, not just young, healthy people buying insurance on their own.

"Even patients with insurance are feeling the pinch and have been reducing their use of health care," Kleinrock said.

The report notes that out-of-pocket costs, which exclude monthly health plan premiums, are now three times higher than they were five years ago, on average. They're seven times higher for those with consumer-driven plans.

That's one reason the number of doctor visits, planned hospital admissions and outpatient treatments each dipped by a half-percent to 1 percent last year, compared with 2011.

At the same time, the number of patients admitted to hospitals after coming to the emergency department spiked for the second straight year, climbing nearly 6 percent in 2012. That's a sign some people are waiting until they are very sick to seek medical help.

Meanwhile, the number of prescriptions used per person last year edged down just 0.1 percent. At the same time, the percentage of all prescriptions filled with a generic medicine rose from 80 percent in 2011 to 84 percent last year. Nearly three-quarters of prescriptions filled in 2012 cost patients $10 or less in copayments.

A big reason was new generic versions of some of the pharmaceutical industry's biggest-selling drugs of all time: Lipitor for high cholesterol, Plavix for preventing blood clots and strokes, Singulair for allergies and asthma, Diovan for high blood pressure and several others.

Those brand-name drugs all lost patent protection during 2012 or late 2011, enabling generic drug companies to flood the market with copycat pills costing up to 90 percent less.

Those new generics reduced spending on medicines by $28.9 billion last year. That savings was partly offset by the introduction of a big number of breakthrough drugs that are very expensive, drugmakers raising prices on existing medicines and population growth.

IMS, based in Parsippany, N.J., compiles and analyzes data from pharmacies, hospitals, nursing homes, drug wholesalers and other groups to produce its annual report on health care spending trends.

Back in 1957, the first year IMS studied, total U.S. drug spending was only $1.9 billion. That's risen each year since, generally climbing more in years when the economy is strong.

For now, IMS is forecasting that overall spending on health care will continue to grow faster than spending on medicines at least through 2017. That's due to factors including the increasing number of elderly patients and those with very expensive chronic conditions such as diabetes, psychiatric disorders, severe heart disease and various cancers.

"The sickest people drive most of our health care spending," Kleinrock said, noting that just over half the total spending by private health insurance plans last year was for just 5 percent of their members.

___

Linda A. Johnson at http://twitter.comLindaJ_onPharma

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-05-09-Prescription%20Spending%20Decline/id-1c6bcce7b10f48d6a8b2245fc774c415

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How to turn off the new persistent Facebook notification

Facebook Settings

Wade through the tangled mess of Facebook notification settings

Facebook likes to do a lot of "opt out" rather than "opt in" changes on its app updates, and the most recent culprit is a new persistent notification for users to keep up with their Facebook notifications at all times. The notification will pop up when you first install the new version of the Facebook app, and will stay in your bar until you tap part of it to enter the app or tap a small "x" on the right side to dismiss it, much like notifications from media players. Unfortunately, it will keep coming back if you don't go change the settings in the Facebook app. To disable it, open your Facebook app, tap "menu" (or the soft menu key) and tap into the Facebook settings. Scroll down to the very bottom of the list, where under "Advanced Notification Settings" you should see an option to uncheck "Ongoing notifications". (Some users report not seeing the setting, which we have yet to figure out the reason behind.)

While you're in there, you can also choose to disable any other notification from Facebook. This will be especially important if you happen to like the ongoing notification, because if you keep the other notifications turned on you will receive two Facebook notifications any time that something happens. We know, Facebook's settings are a mess, but if you're going to keep the app installed the least you can do is keep the notifications in check.

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/suOaB2671Mw/story01.htm

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Thursday, March 28, 2013

In order to omit needless words and cut deadwood

Wherein the Monitor?s language columnist vents a bit on redundancies she loves to hate, but also warns wordsmiths against turning into 'search-and-replace' editors.

By Ruth Walker / March 28, 2013

I was reviewing the work of an esteemed colleague, collating her corrections of our manuscript and those of our author, when I noticed a lot of striking through of the first two words of a usually unremarkable three-word phrase: "in order to."

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Hmm, she seems not to like "in order," I thought. At all.

There was perhaps a bit of professional jealousy involved. My colleague obviously had a spiffier version than I of our annotation software. Hers let her strike through offending words incontrovertibly, as with a red ballpoint and a ruler. Take that! And that!

But back to "in order to": Is it always deadwood?

As it happens, Copyediting, the newsletter, ran an item recently on this raging controversy in its weekly tips column, and took a nuanced position. In a sentence such as, "In order to control class sizes, the district will also place seven portable classrooms at the four schools," the "in order" should be trimmed, in the great Strunk & White tradition of omitting needless words.

But the Copyediting columnist, Erin Brenner, cited Bryan Garner's "Modern American Usage" as saying that "in order to," while wordy, can be useful in sentences in which there is already an infinitive.

To cite Mr. Garner's own example: "The controversy illustrates how the forces of political correctness pressure government to grow in size and arbitrariness in order to pursue a peculiar compassion mission."

Ms. Brenner, though, thinks there's more to it than that. "In order to" isn't just an extra little verbal ruffle; it's an established idiom meaning "for the purpose of." It's a much-used idiom at that. Often the "in order" is out of order, but sometimes it's needed.

For example: "We the People of the United States, in Order to form a more perfect Union..."

That's my example, not Brenner's; but the sense of "purpose" comes through there ? along with the repetition of the three "or" sounds ("order ... form ... more"). And the rhythm would be wrong without "in order."

Another editor I've much admired once commented: "You don't want to be a 'search-and-replace' editor." That is, do more for your writers than just execute a string of reflexive deletions.

But I can also hear, with the ear of memory, other editors I've worked with over the years and the redundancies they have pointed out to me: "reason why," as in, "I asked him the reason why he looked so glum." Usually either "reason" or "why" on its own suffices. Or "outside of": "Outside" alone is generally all you need.

The "or not" of "whether of not" is often, though not always, redundant. It's not needed here: "The board is to decide tonight whether or not to fire the president." But it is useful in, for instance, the sentence, "Whether or not he gets the job, he'll still need some new clothes."

I suppose I have redundancies I love to hate, too: "track record" where "record" alone would serve, for instance.

My newest pet peeve is the Roman numeral "I" some are attaching to the name of the new pope. Stop it, everyone, right now, before it becomes a habit. It's entirely unnecessary. He will be Francis I only after he's gone, and a new pope takes the name Francis II. And given that it's taken a couple of millenniums for the Roman Catholic Church to have its first Pope Francis, we needn't hold our breath for a second one anytime soon.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/aaDTvuF6dgU/In-order-to-omit-needless-words-and-cut-deadwood

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Founder Mike Lazaridis to leave Blackberry May 1st as vice-chairman and director

Lazaridis to leave Blackberry as

On the heels of today's earnings release, Blackberry vice chairman Mike Lazaridis announced that he'll leave the company on May 1st. The exec founded the company formerly known as Research in Motion almost 30 years ago, with Jim Balsillie as its early CEO -- who resigned this time last year himself and recently sold off his remaining shares. Lazaridis said that he'll focus instead on his new Quantum Valley Investments venture, which recently backed a research center in his home town of Waterloo, Ontario.

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Source: http://www.engadget.com/2013/03/28/mike-lazaridis-to-leave-blackberry/

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Wednesday, March 20, 2013

Under the skin, a tiny laboratory

Mar. 19, 2013 ? Humans are veritable chemical factories -- we manufacture thousands of substances and transport them, via our blood, throughout our bodies. Some of these substances can be used as indicators of our health status. A team of EPFL scientists has developed a tiny device that can analyze the concentration of these substances in the blood. Implanted just beneath the skin, it can detect up to five proteins and organic acids simultaneously, and then transmit the results directly to a doctor's computer. This method will allow a much more personalized level of care than traditional blood tests can provide. Health care providers will be better able to monitor patients, particularly those with chronic illness or those undergoing chemotherapy. The prototype, still in the experimental stages, has demonstrated that it can reliably detect several commonly traced substances.

The research results will be published and presented March 20, 2013 in Europe's largest electronics conference, DATE 13.

Three cubic millimeters of technology

The device was developed by a team led by EPFL scientists Giovanni de Micheli and Sandro Carrara. The implant, a real gem of concentrated technology, is only a few cubic millimeters in volume but includes five sensors, a radio transmitter and a power delivery system. Outside the body, a battery patch provides 1/10 watt of power, through the patient's skin -- thus there's no need to operate every time the battery needs changing.

Information is routed through a series of stages, from the patient's body to the doctor's computer screen. The implant emits radio waves over a safe frequency. The patch collects the data and transmits them via Bluetooth to a mobile phone, which then sends them to the doctor over the cellular network.

A system that can detect numerous substances

Great care was taken in developing the sensors. To capture the targeted substance in the body -- such as lactate, glucose, or ATP -- each sensor's surface is covered with an enzyme. "Potentially, we could detect just about anything," explains De Micheli. "But the enzymes have a limited lifespan, and we have to design them to last as long as possible." The enzymes currently being tested are good for about a month and a half; that's already long enough for many applications. "In addition, it's very easy to remove and replace the implant, since it's so small."

The electronics were a considerable challenge as well. "It was not easy to get a system like this to work on just a tenth of a watt," de Micheli explains. The researchers also struggled to design the minuscule electrical coil that receives the power from the patch.

Towards personalized chemotherapy

The implant could be particularly useful in chemotherapy applications. Currently, oncologists use occasional blood tests to evaluate their patients' tolerance to a particular treatment dosage. In these conditions, it is very difficult to administer the optimal dose. De Micheli is convinced his system will be an important step towards better, more personalized medicine. "It will allow direct and continuous monitoring based on a patient's individual tolerance, and not on age and weight charts or weekly blood tests."

In patients with chronic illness, the implants could send alerts even before symptoms emerge, and anticipate the need for medication. "In a general sense, our system has enormous potential in cases where the evolution of a pathology needs to be monitored or the tolerance to a treatment tested."

The prototype has already been tested in the laboratory for five different substances, and proved as reliable as traditional analysis methods. The project brought together eletronics experts, computer scientists, doctors and biologists from EPFL, the Istituto di Ricerca di Bellinzona, EMPA and ETHZ. It is part of the Swiss Nano-Tera program, whose goal is to encourage interdisciplinary research in the environmental and medical fields. Researchers hope the system will be commercially available within 4 years.

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The above story is reprinted from materials provided by Ecole Polytechnique F?d?rale de Lausanne, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/HjbSJwuy0Hg/130319202151.htm

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Winter storm slams travel in the Dakotas

FARGO, N.D. (AP) ? A late-winter storm shut down schools and caused travel problems Monday throughout much of North Dakota and eastern South Dakota.

Motorists in many areas were advised not to travel or to use extreme caution because of blowing snow. The wind was forecast to gust up to 60 mph in northeastern South Dakota.

"It doesn't take a whole lot of snow with these strong winds to cause problems," National Weather Service meteorologist Ryan Vipond told the American News in Aberdeen, S.D. Ice also was a problem on roads in the region, according to KELO-TV.

Parts of eastern North Dakota were expecting more than half a foot of snow. The National Weather Service issued a blizzard warning for much of eastern North Dakota and for northeastern and east central South Dakota.

Many schools started late or called off classes for the day. Personnel at Minot Air Force Base in north central North Dakota who were not considered "essential" were allowed to come to work late.

People had to be rescued from more than two dozen stranded vehicles on Interstate 29 between Fargo and Wahpeton in southeastern North Dakota late Sunday and early Monday, Highway Patrol Capt. Bryan Niewind told The Forum newspaper.

The storm occurred a few days ahead of the next NWS outlook for spring flooding, due out Thursday. Hydrologist Mike Lukes told The Associated Press that the additional moisture could increase the risk for flooding in the Red River Valley of eastern North Dakota and northwestern Minnesota.

"We're sitting somewhere between 3, 4, 5, 6 inches of water in the snow already," he said. "Additional (moisture) will add to it, but as far as (the flood risk) going up significantly higher, that probably isn't in the cards."

Lukes estimated the new snow in the southern Red River Valley contained about half an inch of water, and the snow in the northern valley about 3- to 4-tenths of an inch.

This system continues a pattern of winter weather in the area, as Fargo saw several inches of snow Friday. It also was preceded by record cold. The temperature at Grand Forks dropped to minus 18 degrees on Saturday and minus 23 degrees on Sunday ? both city records for those dates.

Source: http://news.yahoo.com/winter-storm-affecting-travel-dakotas-132252593.html

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